|Author:||Andreas Heger, Tildon Grant Belgrad, Martin Goodson, Leo Goodstad, Kevin Jacobs|
|Date:||February 14, 2011|
The SAM/BAM format is a way to store efficiently large numbers of alignments [Li2009], such as those routinely are created by next-generation sequencing methods.
This module provides a low-level wrapper around the samtools C-API using cython and a high-level API for convenient access to the data in SAM/BAM formatted files. Also included is an interface to the tabix C-API for reading compressed and indexed tabular data.
The current version wraps samtools-0.1.12a and tabix-0.2.3.
|[Li2009]||The Sequence Alignment/Map format and SAMtools. Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, Marth G, Abecasis G, Durbin R; 1000 Genome Project Data Processing Subgroup. Bioinformatics. 2009 Aug 15;25(16):2078-9. Epub 2009 Jun 8. PMID: 19505943|